Table 3.
Crude Attributable Mortality of Influenza-Related Hospitalizations in Children With ALL, 1999–2011
| Category | Influenza-Related Hospitalizations (n) | Deaths (n) | Mortality Rate |
P | NNP† | ||
|---|---|---|---|---|---|---|---|
| Influenza-Related Hospitalizations (95% CI) | Noninfluenza Hospitalizations*(95% CI) | Attributable Increase (95% CI) | |||||
| Overall | 629 | 9 | 1.4% (.7–2.7) | 0.4% (.4–0.5) | 1.0% (.3–2.3) | .002 | 100 |
| Time from ALL diagnosis | |||||||
| <6 months | 206 | 4 | 1.9% (.5–2.7) | 0.4% (.3–.4) | 1.6% (.4–4.5) | <.01 | 63 |
| ≥6 months | 423 | 5 | 1.2% (.4–2.7) | 0.6% (.5–.7) | 0.7% (−.1 to 2.2) | .10 | 143 |
| Age category | |||||||
| 0 to <2 years | 27 | 2 | 7.4% (.9–24.3) | 0.7% (.5–1.1) | 6.7% (1.3–22.7) | .02 | 15 |
| 2 to <5 years | 232 | 3 | 1.3% (.3–3.7) | 0.2% (.1–.3) | 1.1% (.2–3.5) | .01 | 91 |
| ≥5 years | 370 | 4 | 1.1% (.3–2.7) | 0.5% (.5–.6) | 0.6% (−.1 to 2.4) | .14 | 167 |
Abbreviations: ALL, acute lymphoblastic leukemia; CI, confidence interval; NNP, number needed to prevent.
*Hospitalizations during the influenza season-adjusted period.
†Decrease in influenza-related hospitalizations needed to prevent 1 death.