Table 4.
Signaling protein(1) |
Pre-surgery signaling versus hip function |
Post-surgery signaling versus hip function |
Pre-surgery versus post- surgery signaling |
|||
---|---|---|---|---|---|---|
R | p value | R | p value | R | p value | |
pMAPKAPK2 | 0.689 | 1.39×10−4 | 0.465 | 1.91×10−2 | 0.570 | 2.87×10−3 |
pCREB | 0.445 | 2.59×10−2 | 0.569 | 2.99×10−3 | 0.589 | 1.93×10−3 |
prpS6 | 0.467 | 1.86×10−2 | 0.591 | 1.88×10−3 | 0.622 | 8.87×10−4 |
Values for pre-surgery signaling are arcsinh ratios in CD14+ monocytes for LPS-stimulated and control samples, and values for post-surgery signaling are arcsinh ratios in CD14+ monocytes for samples collected before surgery and 1 hour after surgery.
Abbreviations: pCREB, phosphorylated cAMP response element-binding protein; pMAPKAPK2, phosphorylated mitogen activated protein kinase-activated protein kinase-2; prpS6, phosphorylated ribosomal protein S6. R, correlation coefficient.