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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Anesthesiology. 2015 Dec;123(6):1241–1255. doi: 10.1097/ALN.0000000000000887

Table 4.

Immune Correlates Pre- and Post-surgery

Signaling
protein(1) 		Pre-surgery signaling
versus hip function		 Post-surgery signaling
versus hip function		 Pre-surgery versus post-
surgery signaling
R p value R p value R p value
pMAPKAPK2 0.689 1.39×10−4 0.465 1.91×10−2 0.570 2.87×10−3
pCREB 0.445 2.59×10−2 0.569 2.99×10−3 0.589 1.93×10−3
prpS6 0.467 1.86×10−2 0.591 1.88×10−3 0.622 8.87×10−4
1)

Values for pre-surgery signaling are arcsinh ratios in CD14+ monocytes for LPS-stimulated and control samples, and values for post-surgery signaling are arcsinh ratios in CD14+ monocytes for samples collected before surgery and 1 hour after surgery.

Abbreviations: pCREB, phosphorylated cAMP response element-binding protein; pMAPKAPK2, phosphorylated mitogen activated protein kinase-activated protein kinase-2; prpS6, phosphorylated ribosomal protein S6. R, correlation coefficient.