Figure 3. Locomotor activity of mice exposed to the open field apparatus after chronic administration of ethanol and stress testing. Mice were tested for 5 min after 14 h of ethanol withdrawal. Data are reported as means±SE. A, Number of quadrants travelled in the periphery of the apparatus; B, number of quadrants travelled in the center of the apparatus; C, number of quadrants travelled in the total area of the apparatus; D, percentage of time spent in the center of the apparatus; E, time spent in each central quadrant. *P<0.05 compared with vehicle-treated groups for n=8-10 animals per group (two-way ANOVA test).
