Table 2. Correlations between percentage change in oxylipin product/fatty acid precursor ratios and fold change in ALOX12 gene expression in response to 6 weeks of supplementation with omega-3 fatty acids as fish oil.
| % Change in Ratio* | P-value | r | Confidence Interval^ |
|---|---|---|---|
| 12-HETE/TG 20:4n6 | 0.0025 | 0.7850 | 0.3842–0.9369 |
| 12-HETE/CE 20:4n6 | 0.0042 | 0.7591 | 0.3281–0.9285 |
| 12-HETE/FFA 20:4n6 | 0.0083 | 0.7200 | 0.2489–0.9156 |
| 12-HETE/PC 20:4n6 | 0.0103 | 0.7060 | 0.2220–0.9108 |
| 12-HETE/LY 20:4n6 | 0.0194 | 0.6606 | 0.1397–0.8951 |
| 12-HETE/PE 20:4n6 | 0.0226 | 0.6484 | 0.1186–0.8908 |
| 12-HETE/DG 20:4n6 | 0.0267 | 0.6344 | 0.0952–0.8858 |
| 12-HEPE/CE 20:5n3 | 0.0036 | 0.7673 | 0.3456–0.9312 |
| 12-HEPE/TG 20:5n3 | 0.0102 | 0.7067 | 0.2235–0.9111 |
| 12-HEPE/LY 20:5n3 | 0.0286 | 0.6285 | 0.0855–0.8837 |
| 12-HEPE/PC 20:5n3 | 0.0304 | 0.6232 | 0.0767–0.8817 |
| 12-HEPE/PE 20:5n3 | 0.0377 | 0.6035 | 0.0452–0.8745 |
*12-HETE: 12-hydroxyeicosatetraenoic acid, 12-HEPE: 12-hydroxyeicosapentaenoic acid, FFA: free fatty acid, LY: lysophosphatidylcholine, PC: phosphatidylcholine, DG: diglyceride, TG: triglyceride, PE: phosphatidylethanolamine
^ 95% Confidence interval for the correlation calculated using the Fischer transformation., CE: cholesterol ester