Figure 2.

Clopidogrel (clop) increases proliferation of mesenchymal stem cells (MSCs). Serial paraffin sections were obtained from buccal-lingual aspects from animals treated with saline solution, aspirin (asp), and clop. The effect on MSC proliferation was measured in the connective tissue by double immunofluorescence assay using CD271- and Ki-67-specific antibodies. (A) Percentage of cells in proliferation (Ki-67⁺). (B) The percent total cells that are double positive for CD271 and Ki67. (C) The percent CD271⁺ cells that are Ki67⁺. Results are from 10 animals/group. Values are expressed as mean ± SEM. Significant difference (P < 0.05) among groups at *baseline and ^#experimental groups.