Table 3. ANOVA for the quadratic model developed for synthesis of KMO ester.
| Source | Sum of Squares | Degree of Freedom | Mean Square | F-value | P-value |
|---|---|---|---|---|---|
| Model | 4660.42 | 11 | 423.67 | 29.20 | <0.0001 |
| Reaction temperature, A | 0.47 | 1 | 0.47 | 0.03 | 0.8600 |
| Reaction time, B | 218.20 | 1 | 218.20 | 15.04 | 0.0015 |
| Enzyme amount, C | 202.79 | 1 | 202.79 | 13.98 | 0.0020 |
| Substrate molar ratio, D | 64.72 | 1 | 64.72 | 4.46 | 0.0519 |
| AC | 581.77 | 1 | 581.77 | 40.10 | < 0.0001 |
| AD | 824.93 | 1 | 824.93 | 56.86 | < 0.0001 |
| BC | 205.89 | 1 | 205.89 | 14.19 | 0.0019 |
| CD | 330.35 | 1 | 330.35 | 22.77 | 0.0002 |
| B 2 | 642.97 | 1 | 642.97 | 44.32 | < 0.0001 |
| C 2 | 94.42 | 1 | 94.42 | 6.51 | 0.0221 |
| D 2 | 1207.33 | 1 | 1207.33 | 83.22 | < 0.0001 |
| Residual | 217.61 | 15 | 14.51 | - | - |
| Lack-of-fit | 122.31 | 10 | 12.23 | 0.64 | 0.7429 |
| Pure error | 95.30 | 5 | 19.06 | - | - |
| Corrected total | 4878.03 | 26 | - | - | - |