Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The ability of FoxA2 to induce Arx expression is dependent on its activation domain. Constructs containing FoxA2, FoxA2ΔA (transcription activation domain deleted) or FoxA2ΔR (transcription repression domain deleted) were electroporated into the developing chick neural tube. Both the FoxA2 and the FoxA2ΔR expression constructs were able to induce the expression of Arx and Nkx2.2. In contrast, FoxA2ΔA failed to induce their expression. Scale bar in upper left panel is 50 μm.
