Table 2:
Multivariable logistic regression
Carotid-IPH Predictor | IPH+ (n = 65) | IPH− (n = 661) | OR | P Value | 95% CI | |
---|---|---|---|---|---|---|
Cardiovascular risk factors | ||||||
Male sex (No./total No.) (%) | 55/65 (70.0) | 332/661 (50.2) | 3.05 | .104 | 0.79 | 11.7 |
Age (yr) (mean) (SD) | 76.0 (9.7) | 63.1 (15.6) | 1.11 | .003 | 1.04 | 1.19 |
BMI (yr) (mean) (kg/m2) | 26.8 (4.0) | 28.5 (6.6) | 0.94 | .325 | 0.84 | 1.06 |
Smoking (No./total No.) (%) | ||||||
Current smoker | 12/65 (18.5) | 126/661 (19.1) | 1.52 | .620 | 0.29 | 7.88 |
Prior smoker | 24/65 (36.9) | 134/661 (20.3) | 1.74 | .399 | 0.48 | 6.36 |
Hypertension (No./total No.) (%) | 46/65 (70.8) | 453/661 (68.5) | 0.30 | .126 | 0.06 | 1.41 |
Hyperlipidemia (No./total No.) (%) | 46/65 (70.8) | 312/661 (47.2) | 1.08 | .895 | 0.33 | 3.62 |
Diabetes (No./total No.) (%) | 23/65 (35.4) | 204/661 (30.9) | 1.04 | .948 | 0.33 | 3.30 |
Cardiovascular medications (No./total No.) (%) | ||||||
Antihypertension | 43/65 (66.2) | 369/661 (55.8) | 2.70 | .170 | 0.65 | 11.1 |
Statin | 42/65 (64.6) | 274/661 (41.5) | 1.24 | .749 | 0.33 | 4.70 |
Antiplatelet | 38/65 (58.5) | 256/661 (38.7) | 1.07 | .922 | 0.29 | 3.88 |
Anticoagulation | 7/65 (10.8) | 67/661 (10.1) | 0.63 | .628 | 0.10 | 4.00 |
Carotid plaque imaging markers | ||||||
Stenosis (mean) (SD) (%) | 46.5 (30.1) | 8.9 (19.3) | .09 | .409 | 0.0003 | 25.7 |
Stenosis (mean) (SD) (mm) | 2.5 (1.5) | 4.3 (1.0) | 0.31 | .052 | 0.09 | 1.01 |
Maximum plaque thickness (mean) (SD) (mm) | 5.4 (1.9) | 2.8 (1.4) | 2.26 | <.001 | 0.09 | 1.01 |
Ulceration (No./total No.) (%) | 34/65 (52.3) | 62/661 (9.4) | 4.36 | .017 | 1.30 | 14.7 |
Intraluminal thrombus (No./total No.) (%) | 5/65 (7.7) | 14/661 (2.1) | 0.49 | .496 | 0.06 | 3.85 |
Magnet strength = 3T (No./total No.) (%) | 16/65 (24.6) | 42/661 (6.4) | 1.63 | .544 | 0.34 | 7.82 |
Note:—BMI indicates body mass index.