. Author manuscript; available in PMC: 2017 Jan 1.

Published in final edited form as: Anesthesiology. 2016 Jan;124(1):121–131. doi: 10.1097/ALN.0000000000000916

Table 2.

Markers of lung injury at baseline (after acid aspiration) and after two hours of moderate tidal volume ventilation. Rats with propagation of lung injury were analyzed separately from those with more contained injury. Vertical distribution of lung injury was quantified by dividing partial scores measured in central over peripheral areas of interest. C: compliance EELV: end expiratory lung volume.

	Propagation (n=6)		Containment (n=9)

	Baseline	2 hrs	Baseline	2 hrs

Body weight (g)	361 ± 26	-	349 ± 26 g	-
*PaO₂ (mmHg)*	421.5 ± 72.1	80.2 ± 25.1 ^‡	451.2 ± 59.4	278.5 ± 158.3 ^†
*Lung Weight (grams)*	4.29 ± 0.21	5.73 ± 1.09 ^†	4.30 ± 0.59	4.36 ± 1.04 ^§
*C(ml/cmH₂O)*	0.21 ± 0.03	0.14 ± 0.02 ^‡	0.25± 0.03	0.21 ±0.03 ^§ ^‡
*EELV(ml)*	2.92 ± 0.30	0.90 ± 0.73 ^‡	3.99 ± 0.78 ^*	3.20 ± 0.44 ^§ ^‡
*Lung Strain*	1.52 ± 0.13	-	1.16 ± 0.20 ^§	-
*Injury Score*	39.3±12.0	154.8 ± 45.1 ^‡	36.5 ± 9.4	51.0 ± 16.0 ^§ ^‡
*Dorsal/ventral score*	3.6 ± 0.8	1.4 ± 0.6 ^‡	4.8 ± 4.1	3.6 ± 3.2

: P<0.05 and

^§

: P<0.01 between groups.

^†

: P<0.05 and

^‡

: P< 0.01 vs Baseline.