Table 1. Demographic and Clinical Characteristics.
| PROBANDS | RELATIVES | |||||||
|---|---|---|---|---|---|---|---|---|
| Controls N=305 | SZ N=265 | SZAFF N=178 | BP N=231 | SZ N=314 | SZAFF N=227 | BP N=274 | Statistics | |
| Age, Mean (SD) | 36.5 (12.4) | 34.5 (12.5) | 36.3 (11.6) | 36 (13.0) | 43 (15.5) | 40.2 (16.1) | 40.9 (15.7) | F(6 1787)=13.7; p<0.001 |
| Sex (% Male) | 45% | 67% | 40% | 35% | 29% | 31% | 36% | X2(6)=112.1; p<0.001 |
| Race | ||||||||
| % Caucasia n | 63% | 46% | 55% | 73% | 55% | 61% | 80% | X2(6)=92.4; p<0.001 |
| % African American | 27% | 45% | 40% | 22% | 40% | 24% | 15% | X2(6)=85.7; p<0.001 |
| % Other | 10% | 9% | 5% | 5% | 5% | 5% | 5% | X2(6)=15.7; p=0.02 |
| Cognitive Assessments, Mean (SD) | ||||||||
| WRAT 41 | 103.8 (14) | 94.9 (16) | 96.7 (14.9) | 101.6 (13.6) | 97.5 (14.7) | 98.9 (16.1) | 103 (14.1) | F(6 1738)=13.6; p<0.001 |
| BACS2 | 0.0 (1.0) | -1.8 (1.4) | -1.5 (1.3) | -0.9 (1.3) | -0.6 (1.2) | -0.6 (1.4) | -0.2 (1.2) | F(6 1682)=73.5; p<0.001 |
| Relatives' Psychotic Disorders and Psychosis Spectrum Personality Traits, N (%) | ||||||||
| Psychotic Disorder | 22 (7%) | 27 (12%) | 21 (8%) | n.s. | ||||
| Psychosis Spectrum Personality Traits3 | 47 (15%) | 32 (14%) | 36 (13%) | n.s. | ||||
| No Psychosis Spectrum Personality Traits | 238 (78%) | 165 (74%) | 214 (79%) | n.s. | ||||
1
Wide Range Achievement Test 4th - Edition: Reading (Wilkinson et al., 2006)
2
Brief Assessment of Cognition in Schizophrenia (Keefe et al., 2008), z-scores are given
3
as defined by meeting full or within one criteria of a Cluster A personality disorder diagnosis (SID-P)