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. Author manuscript; available in PMC: 2016 Dec 15.
Published in final edited form as: Cancer Res. 2015 Dec 2;75(24):5392–5397. doi: 10.1158/0008-5472.CAN-15-1706

Figure 1. Stem cell targeted Cre recombination assessed by crossing Lgr5CreERT2 with Rosa26-LacZ mice.

Figure 1

A. Representative images of X-gal staining with no tamoxifen, and 1, 5, and 12 days post tamoxifen (1 mg) injection. X-gal staining (blue) after 1 tamoxifen injection indicates Cre recombinase activity at the crypt base. Days 5 and 12 denote lineage tracing. B. Percentage of crypts expressing Cre recombinase activity 1, 5, and 12 days post tamoxifen injection (means from 3 mice).