Table 1. Blood biochemical parameters after 30 days receiving saline (C and D groups), L-glutamine (G) or glutamine dipeptide (GDP) in non diabetic rats (C group), and diabetic rats (D).
The animais were distributed in six groups: C, D, CG, DG, CGDP, and DGDP.
| C | D | CG | DG | CGDP | DGDP | |
|---|---|---|---|---|---|---|
| Fasting glucose (mg/dL) | 76.6±3.0 | 385.8±10.2* | 67±2.5 | 417.0±31.3 | 82.0±2.9 | 394.6±20.7 |
| Fructosamine (mmol/L) | 0.88±0.02 | 1.55±0.08* | 0.62±0.04 | 1.62±0.07 | 0.72±0.04 | 1.18±0.05# |
| AST (U/L) | 41.15±2.7 | 205.40±36.1* | 64.57±6.9 | 104.40±8.27 | 69.21±10.1 | 135.90±13.2 |
| ALT (U/L) | 12.08±1.3 | 232.30±33.7* | 13.16±0.7 | 122.90±13.2# | 21.80±1.8 | 260.30±14.3 |
| Triglycerides (mg/dL) | 28.50±1.2 | 71.38±7.8* | 59.13±3.3 | 42.63±5.9# | 58.70±11.0 | 71.83±10.2 |
| Total cholesterol (mg/dL) | 62.37±4.2 | 44.41±1.3 | 73.32±5.3 | 61.13±5.3# | 86.35±1.3* | 45.72±2.9 |
| HDL cholesterol (mg/dL) | 43.63±1.7 | 23.63±1.2* | 38.63±1.5 | 38.13±3.8# | 43.60±2.3 | 28.90±2.1 |
| Total protein (mg/dL) | 5.93±0.1 | 5.43±0.2 | 5.39±0.08 | 5.77±0.2 | 6.42±0.1 | 5.67±0.3 |
| Ammonia (mg/dL) | 3.05±0.06 | 3.42±0.1 | 3.05±0.08 | 3.236±0.2 | 2.89±0.1 | 2.73±0.2 |
| Urea (mg/dL) | 24.21±0.7 | 66.91±1.8* | 30.69±1.5 | 58.97±1.8 | 30.86±2.7 | 66.87±3.2 |
Results expressed as mean±SEM (n = 5/group).
* p<0.05 vs. C group
# p<0.05 vs. D group
one-way ANOVA and Tukey post test.