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Cytotoxcities of the isolates on six cancer cell lines with IC50 values (μM)
| Compounda | HeLa | KB-3-1 | NCI-H 460 | PC3 | MCF-7 | K562 |
|---|---|---|---|---|---|---|
| 5 | 7.7 | 7.7 | 7.4 | 6.0 | 8.7 | 5.0 |
| 6 | 10.9 | 9.1 | 8.9 | 10.5 | 11.4 | 6.7 |
| 7 | >20 | >20 | 17.2 | >20 | >20 | 15.9 |
| 9 | 16.7 | 12.8 | >20 | 5.2 | >20 | 6.1 |
| 11 | 10.1 | 9.2 | >20 | 8.9 | >20 | 5.5 |
| 12 | 17.1 | 10.3 | >20 | >20 | >20 | 13.6 |
| Paclitaxelb | 0.01 | 0.003 | 0.004 | 0.007 | 0.21 | 0.005 |
aOther selected ones not listed in the table were inactive (IC50 > 20 μM) for all cell lines
bPaclitaxel was used as positive controls
