Fig. 3.

Effect of Kit ligand on Foxo3 oocyte localization. a Incubation of explanted ovaries at PD7 with kit ligand (KL) at 150 ng/mL for 60–90 min resulted in decreased proportion of oocytes with nuclear Foxo3 as compared to controls (59 vs. 25 %, p = 0.03, based on t test), along with a reciprocal increase in proportion of oocytes with cytoplasmic Foxo3. Error bars = SEM. b Matched pair experimental design with additional samples again showed changes in subcellular localization that were statistically significant (p value based on two-tailed paired t test)