Table 4. Comparisons of Gleason score on second biopsy among the benign diagnosis, HGPIN, and ASAP groups.

	Total	Pathologic findings on first biopsy			p-value
		Benign diagnosis	HGPIN	ASAP
Gleason score					0.324
6	116 (54.2)	85 (51.8)	19 (57.6)	12 (70.6)
7	68 (31.8)	52 (31.7)	12 (36.4)	4 (23.5)
8	30 (14.0)	27 (16.5)	2 (6.1)	1 (5.9)

Values are presented as number (%).

Unfavorable disease, Gleason score≥8, pathologic stage≥T3b (involving the seminal vesicle), and/or spread to regional lymph nodes after radical prostatectomy.

HGPIN, high-grade prostatic intraepithelial neoplasia; ASAP, atypical small acinar proliferation.