Figure 2.

Depiction of the four elementary workflow steps. Arrows indicate influences on a particular workflow step to another one. After the model definition (W1) is concluded simulation (W2) is performed. Next, simulation artifacts are post-processed (W3) and passed to the analysis step (W4). Analysis influences the post-processing step whenever, e.g., a new statistical measure is needed to assess system behavior. Analysis also effects the model definition, e.g., to converge the model to biological findings.