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An overview of the three major EV subtypes. The biogenesis of these different subtypes of EVs is illustrated. Exosomes (blue) and MVs (yellow) are released from a living cell (blue) by fusion of multivesicular bodies (MVBs) with the plasma membrane or budding of the plasma membrane, respectively. Apoptotic bodies are released from a cell undergoing apoptosis (red). Selected physical and phenotypical differences between the three subtypes are depicted.
