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. 2015 Dec 14;10(12):e0144904. doi: 10.1371/journal.pone.0144904

Table 1. Effect of LTBI status and PPD stimulation on target gene expression.

LTBI+ vs LTBI- (PPD stimulation) LTBI+ vs LTBI- (No stimulation)
Target gene Ratio of proportions [C.I.] p-value Ratio of proportions [C.I.] p-value
GFP 1.2 [0.7, 2.1] 0.58 1.2 [0.7, 2.1] 0.38
IFNG 2.5 [1.5, 4.3] <0.001 0.7 [0.4, 1.1] 0.11
IL2 2.9 [1.5, 5.7] <0.002 1.0 [0.6, 1.5] 0.95

Ratios of proportions of mRNA+CD3+ cells are shown in LTBI+ vs. LTBI- donors by PPD stimulation. Ratios of proportions and associated confidence intervals (C.I.) and p-values were calculated using a Poisson regression model, with a log-link adjusted for the total number of CD3+ cells.