Figure 3.

From TNM to TNM-I in SCC NSCLC.

DSS curves of the SCC patient subgroup, according to (A) pathological (TNM) stage and (B) immunoscore (combination of T-CD45RO and S-CD8 score). The combination of A and B results in a “TNM-I” survival table (C) identifying subgroups of patients with greatly differing 5-year DSS within the same pathological stages. The colors of the boxes in the table (C) represent patient subgroups with similar survival [favorable prognosis (green), intermediate-favorable prognosis (light green), intermediate-poor prognosis (gray), poor prognosis (red)]. Constructing survival curves (DSS) for these patient subgroups (D) illustrates how the immunoscore adds significant prognostic impact across each pathological stage.