Table 1. Residues related to antigen–antibody binding.
TRAIL-R2 |
|
KMTR2 |
||||||
---|---|---|---|---|---|---|---|---|
epitope | residue | atom | distance | atom | residue | CDR | chain | |
1 | Ilu87 | Cγ2 | 3.73 | Cβ | Trp94 | 3 | L | |
Glu89 | O | 2.96 | h | Nε1 | Trp50 | 2 | H | |
Cδ | 3.89 | Cε | Lys33 | 1 | ||||
Oε1 | 3.07 | h | Nζ | |||||
2.72 | h | N | Gly103 | 3 | ||||
Oε2 | 3.24 | h | Nζ | Lys33 | 1 | |||
water mediated | h | Nε1 | Trp50 | 2 | ||||
water mediated | h | N | Asn52 | |||||
water mediated | h | Oγ | Ser57 | |||||
Asp90 | N | water mediated | h | O | Thr58 | |||
Cβ | 3.84 | Cα | Gly59 | |||||
C | 3.91 | Cε2 | Trp94 | 3 | L | |||
Gly91 | Cα | 3.61 | Cδ1 | |||||
2 | Asp102 | Oδ2 | 2.97 | h | Nη1 | Arg107 | 3 | H |
water mediated | h | Nη2 | ||||||
His106 | Nε2 | water mediated | h | Nε2 | Gln27 | 1 | L | |
water mediated | h | Nδ2 | Asm93 | 3 | ||||
Asp109 | N | water mediated | h | |||||
O | 2.85 | h | N | Trp94 | ||||
Oδ1 | 2.65 | h | Nδ2 | Asn93 | ||||
Oδ2 | water mediated | h | O | Trp94 | ||||
water mediated | h | N | Glu1 | ─ | ||||
Leu111 | N | 2.87 | h | O | Ser92 | 3 | ||
Cβ | 3.96 | Cε1 | Tyr106 | 3 | H | |||
Cδ1 | 3.82 | Cβ | Trp94 | 3 | L | |||
Cδ2 | 3.67 | C | Asn93 | |||||
3.70 | Cδ1 | Leu96 | ||||||
Phe112 | Cδ1 | 3.71 | Cδ1 | Tyr106 | 3 | H | ||
3.55 | Cβ | Arg107 | ||||||
Cε2 | 3.52 | Cε1 | Tyr32 | 1 | L | |||
Cζ | 3.73 | Cα | Ser92 | 3 | ||||
Cys113 | O | 2.78 | h | Nη1 | Arg107 | 3 | H | |
Arg115 | N | water mediated | h | Oη | Tyr32 | 1 | L | |
Cγ | 3.27 | Cζ | Arg107 | 3 | H | |||
Nη1 | 3.24 | h | Oδ2 | Arg108 | ||||
water mediated | h | Oη | Tyr32 | 1 | L | |||
water mediated | h | O | Arg107 | 3 | H |
h: hydrogen bond (within 3.6 Å between donor and acceptor).