Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 17;5:18311. doi: 10.1038/srep18311

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) The inner medulla sections of control rats (C) and rats fed with a potassium-free diet for 1 day (NK) were triple-labeled against AQP2 (red), Lamp1 (pink), and LC3 (green). Insets demonstrate significant co-localization as a group of puncta, which were not observed in control sections. Scale bar = 4 μm. (B) Representative scatter plots demonstrate the high degree of co-localization between AQP2 and LC3 (r² = 0.83, P < 0.05) or Lamp1 (r² = 0.73, P < 0.05) after potassium deprivation. (C) A bar graph summarizes Pearson correlation coefficients of AQP2 and LC3 or Lamp1. (D) By immunogold EM, AQP2 (small gold particles, arrows) and LC3β (large gold particles, arrow heads) localize in autophagosomes in IMCD cells of potassium-deprived rats. (E) AQP2 (small gold particles, arrows) and cathepsin-D (large gold particles, arrow heads) also localize in similar membrane-bound organelles.