Table 1. A list of cell-cell adhesion and cytoskeleton related proteins which correlate with proteomic analysis and kidney histopathology.
Functions | Proteins |
---|---|
Cadherin-based adherens | β-catenin (Cttnb1)*, vinculin (Vcl)*, cadherin-16 (Cdh16), α-actinin-4 (Actn4) |
Focal adhesion protein | integrin β-1 (Itgb1)*, vinculin (Vcl)*, filamin-B (Flnb), α-actinin-4 (Actn4) |
Actin cytoskeleton organization | ezrin (Ezr)*, transforming protein RhoA precursor (RhoA)*, integrin β-1 (Itgb1)*, calreticulin precursor (Calr), EH domain-containing protein 2 (Ehd2), keratin, type I cytoskeletal 19 (Krt19), spectrin alpha chain, non-erythrocytic 1 (Sptan1), ras-related protein Ral-A (Rala) |
*Proteins co-localized with AQP2 and Lamp1 in IMCD of potassium-deprived rats as demonstrated by immunofluorescence in this study.