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. 2015 Dec 9;6:8885. doi: 10.1038/ncomms9885

Table 2. Significant phenome-wide associations.

X class X variable Y class Y variable r t N P(BF)
behav Alcohol intake (previous evening) fullmetab Butane-2,3-diol 0.792 7.38 40 0.0000
bwcorr Visual-2-visual-1 behav Fatigue (after scan) 0.400 5.10 74 0.0129
bwcorr Visual-2-dorsal attention behav Fatigue (after scan) 0.496 5.06 74 0.0157
bwcorr Visual-1-cingulo-opercular behav Fatigue (after scan) 0.621 6.81 74 0.0000
bwcorr Somatomotor-medial parietal behav TuesThurs 0.532 5.34 72 0.0036
food Cashews fullmetab Glutamine 0.553 5.29 39 0.0048
food Eggs fullmetab N-methylalanine 0.428 5.07 39 0.0152
food Bacon metab C15: no enrichment 0.616 5.80 39 0.0002
food Olives wgcna ME16: no enrichment 0.464 5.88 39 0.0002
fullmetab Glutamic acid bwcorr DMN-visual-1 0.574 4.94 39 0.0293
fullmetab Beta-alanine bwcorr Visual-2-fronto-parietal 0.527 5.17 39 0.0092
fullmetab Aminomalonate bwcorr DMN-somatomotor 0.496 5.27 39 0.0052
immport Antimicrobials bwcorr Salience-cingulo-opercular 0.452 4.84 39 0.0491
metab C13:retinol biosynthesis bwcorr Visual-2-dorsal attention 0.505 4.84 39 0.0497
wgcna ME45:no enrichment bwcorr Visual-2-parieto-occipital 0.353 4.84 39 0.0499
wgcna ME52:protein catabolic process bwcorr Fronto-parietal-somatomotor 0.385 5.13 39 0.0113
wgcna ME60:no enrichment bwcorr Fronto-parietal-somatomotor 0.473 5.83 39 0.0002
wgcna ME28:no enrichment fullmetab Uric acid 0.502 4.93 48 0.0308
wincorr Visual-2 wincorr Somatomotor 0.553 5.98 84 0.0001
wincorr Visual-1 wincorr Somatomotor 0.478 5.22 84 0.0067
wincorr Somatomotor wincorr Visual-1 0.478 4.88 84 0.0414

r, Pearson's correlation between variables; t, t-statistic from time-series regression; N, number of observations entering analysis; P (BF), Bonferroni-corrected P value. A listing of the strongest associations between measures across the entire data set, sorted by the X variable class. All tests listed here were significant after the Bonferroni correction for all 38,363 tests. Variable classes are abbreviated as: wincor, within-network connectivity; bwcorr, between-network connectivity; netdat, graph–theoretic measures on brain connectivity; gene, gene expression modules; metab, metabolite modules; fullmetab, individual metabolites; behav, behavioural/self-report measures.