Table 2. Significant phenome-wide associations.
X class | X variable | Y class | Y variable | r | t | N | P(BF) |
---|---|---|---|---|---|---|---|
behav | Alcohol intake (previous evening) | fullmetab | Butane-2,3-diol | 0.792 | 7.38 | 40 | 0.0000 |
bwcorr | Visual-2-visual-1 | behav | Fatigue (after scan) | 0.400 | 5.10 | 74 | 0.0129 |
bwcorr | Visual-2-dorsal attention | behav | Fatigue (after scan) | 0.496 | 5.06 | 74 | 0.0157 |
bwcorr | Visual-1-cingulo-opercular | behav | Fatigue (after scan) | 0.621 | 6.81 | 74 | 0.0000 |
bwcorr | Somatomotor-medial parietal | behav | TuesThurs | 0.532 | 5.34 | 72 | 0.0036 |
food | Cashews | fullmetab | Glutamine | 0.553 | 5.29 | 39 | 0.0048 |
food | Eggs | fullmetab | N-methylalanine | 0.428 | 5.07 | 39 | 0.0152 |
food | Bacon | metab | C15: no enrichment | 0.616 | 5.80 | 39 | 0.0002 |
food | Olives | wgcna | ME16: no enrichment | 0.464 | 5.88 | 39 | 0.0002 |
fullmetab | Glutamic acid | bwcorr | DMN-visual-1 | 0.574 | 4.94 | 39 | 0.0293 |
fullmetab | Beta-alanine | bwcorr | Visual-2-fronto-parietal | 0.527 | 5.17 | 39 | 0.0092 |
fullmetab | Aminomalonate | bwcorr | DMN-somatomotor | 0.496 | 5.27 | 39 | 0.0052 |
immport | Antimicrobials | bwcorr | Salience-cingulo-opercular | 0.452 | 4.84 | 39 | 0.0491 |
metab | C13:retinol biosynthesis | bwcorr | Visual-2-dorsal attention | 0.505 | 4.84 | 39 | 0.0497 |
wgcna | ME45:no enrichment | bwcorr | Visual-2-parieto-occipital | 0.353 | 4.84 | 39 | 0.0499 |
wgcna | ME52:protein catabolic process | bwcorr | Fronto-parietal-somatomotor | 0.385 | 5.13 | 39 | 0.0113 |
wgcna | ME60:no enrichment | bwcorr | Fronto-parietal-somatomotor | 0.473 | 5.83 | 39 | 0.0002 |
wgcna | ME28:no enrichment | fullmetab | Uric acid | 0.502 | 4.93 | 48 | 0.0308 |
wincorr | Visual-2 | wincorr | Somatomotor | 0.553 | 5.98 | 84 | 0.0001 |
wincorr | Visual-1 | wincorr | Somatomotor | 0.478 | 5.22 | 84 | 0.0067 |
wincorr | Somatomotor | wincorr | Visual-1 | 0.478 | 4.88 | 84 | 0.0414 |
r, Pearson's correlation between variables; t, t-statistic from time-series regression; N, number of observations entering analysis; P (BF), Bonferroni-corrected P value. A listing of the strongest associations between measures across the entire data set, sorted by the X variable class. All tests listed here were significant after the Bonferroni correction for all 38,363 tests. Variable classes are abbreviated as: wincor, within-network connectivity; bwcorr, between-network connectivity; netdat, graph–theoretic measures on brain connectivity; gene, gene expression modules; metab, metabolite modules; fullmetab, individual metabolites; behav, behavioural/self-report measures.