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. 2015 Dec 16;15:965. doi: 10.1186/s12885-015-1960-z

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© Pei et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — PMS inhibited tumor metastasis via decreasing angiogenesis. The complete lungs were fixed after autopsy and the number of lung metastases foci (arrow) was counted (a). b Quantitative analysis of metastases corresponding to the images in a. Paraffin-embedded sections of control or treated lung tissues from mice were analyzed by (c) H&E staining (Scale bar = 100 μm) and analyzed by (d) Ki67 IHC staining(Scale bar = 25 μm). e and f Quantitative analysis of metastases or Ki67 staining corresponding to the images in a and b respectively. Data represent the mean ± S.D. of three independent experiments. g Paraffin-embedded sections of control or treated tumor tissues from mice were analyzed by CD31 IHC staining. Scale bar = 25 μm. h Quantitative analysis of CD31 staining corresponding to the images in g. Data represent the mean ± S.D. of three independent experiments. The ** indicates significance different. The *** indicates extremely significance different