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. 2015 Dec 16;15:963. doi: 10.1186/s12885-015-1770-3

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© Lebok et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Examples of FISH findings using the PTEN deletion probe. a Normal PTEN copy numbers as indicated by two orange PTEN signals and two green centromere 10 signals. b Heterozygous deletion as indicated by the lack of one orange PTEN signal and two green centromere 10 signals. c Homozygous deletion as indicated by the complete absence of orange PTEN signals and the presents of two centromere 10 signals in all tumor cells