Figure 1.

Peripherin-Positive Sensory Neurons at 4 and 6 Weeks of Differentiation

(A) Control and PD iPSCs acquired a βIII tubulin+ (green)/peripherin+ (red) sensory neuron phenotype. Nuclei are labeled with Hoechst (blue).

(B and C) Quantification of peripherin+ (B) and βIII tubulin+ (C) sensory neurons showed no significant difference in neuronal differentiation efficiency between control and PD iPSCs.

(D) There was no difference in neurite length between control and PD iPSC-derived sensory neurons.

n.s., not significant by one-way ANOVA at each time point; n = 6 independent experiments. The scale bar represents 50 μm. See also Figure S1.