Figure 2.

LRRK2 G2019S iPSC-Derived Sensory Neurons Display Neurite Aggregate Formation

(A) LRRK2 G2019S sensory neurons showed abnormal neurite patterns and increased aggregates along the neurites (white arrows).

(B) The number of aggregates per neurite was significantly increased in LRRK2 G2019S neurons compared to all other groups by one-way ANOVA within each time point.

(C) The aggregate area was significantly increased in both LRRK2 G2019S 1 and 2 compared to all other groups by Kruskal-Wallis test.

^∗p < 0.01; n = 4 independent experiments. The scale bar represents 50 μm. See also Figure S2.