Table 2.
MED12 mutation | African American (68) | Caucasian (43) | Hispanic (24) |
---|---|---|---|
c.130G > A | 5/10 (50 %) | 4/10 (40 %) | 1/10 (10 %) |
c.130G > T | 2/4 (50 %) | 2/4 (50 %) | 0/4 (0 %) |
c.130G > C | 4/4 (100 %) | 0/4 (0 %) | 0/4 (0 %) |
c.131G > A | 19/31 (61.3 %) | 7/31 (22.5 %) | 5/31 (16.1 %) |
c.131G > T | 1/1 (100 %) | 0/1 (0 %) | 0/1 (0 %) |
c.131G > C | 2/2 (100 %) | 0/2 (0 %) | 0/2 (0 %) |
c.107T > C | 2/4 (50 %) | 1/4 (25 %) | 1/4 (25 %) |
c.107T > G | 0/2 (0 %) | 2/2 (100 %) | 0/2 (0 %) |
c.108G > C | 0/1 (0 %) | 0/1 (0 %) | 1/1 (100 %) |
c.108G > T | 0/2 (0 %) | 0/2 (0 %) | 2/2 (100 %) |
Deletions | 10/24 (41.6 %) | 10/24 (41.6 %) | 3/24 (12.5 %) |
No mutations | 23/53 (43.3 %) | 17/53 (32.1 %) | 11/53 (20.7 %) |
The mutation status in exon 2 of the MED12 gene in the different ethnic groups including African American, Caucasian, and Hispanic from the Southern United States is presented