Table 4.
Enrichment analysis of 179 genes commonly selected in the top most 2000 genes by applying PCA-based unsupervised FE to gene expression and promoter methylation.
| g:profiler GO BP | |||
|---|---|---|---|
| GO:0007606 | 54 | Sensory perception of chemical stimulus | 9.14E-21 |
| GO:0007186 | 65 | G-protein coupled receptor signaling pathway | 7.61E-20 |
| GO:0050911 | 50 | Detection of chemical stimulus involved in sensory perception of smell | 1.44E-19 |
| GO:0007600 | 58 | Sensory perception | 2.89E-19 |
| GO:0050907 | 50 | Detection of chemical stimulus involved in sensory perception | 5.26E-19 |
| GO:0007608 | 50 | Sensory perception of smell | 5.65E-19 |
| GO:0009593 | 50 | Detection of chemical stimulus | 1.72E-18 |
| GO:0050906 | 50 | Detection of stimulus involved in sensory perception | 3.39E-18 |
| GO:0007166 | 84 | Cell surface receptor signaling pathway | 4.19E-18 |
| GO:0003008 | 69 | System process | 8.92E-18 |
| GO:0051606 | 51 | Detection of stimulus | 1.26E-17 |
| GO:0050877 | 59 | Neurological system process | 3.82E-16 |
| GO:0051716 | 106 | Cellular response to stimulus | 6.09E-13 |
| GO:0042221 | 84 | Response to chemical | 9.54E-13 |
| GO:0050896 | 116 | Response to stimulus | 4.65E-12 |
| GO:0007154 | 98 | Cell communication | 4.91E-12 |
| GO:0007165 | 92 | Signal transduction | 2.84E-11 |
| GO:0044700 | 95 | Single organism signaling | 6.05E-11 |
| GO:0023052 | 95 | Signaling | 6.70E-11 |
| GO:0065007 | 131 | Biological regulation | 3.40E-10 |
| GO:0050789 | 128 | Regulation of biological process | 3.48E-10 |
| GO:0050794 | 120 | Regulation of cellular process | 1.92E-07 |
| GO:0044707 | 94 | Single-multicellular organism process | 9.54E-07 |
| GO:0032501 | 94 | Multicellular organismal process | 8.75E-06 |
| GO:0044763 | 129 | Single-organism cellular process | 1.17E-05 |
| GO:0044699 | 135 | Single-organism process | 1.86E-04 |
| GO:0046010 | 3 | Positive regulation of circadian sleep/wake cycle, non-REM sleep | 2.21E-02 |
| GO CC | |||
| GO:0016021 | 88 | Integral component of membrane | 1.13E-12 |
| GO:0031224 | 88 | Intrinsic component of membrane | 3.85E-12 |
| GO:0071944 | 79 | Cell periphery | 1.19E-08 |
| GO:0044425 | 92 | Membrane part | 1.43E-08 |
| GO:0005886 | 77 | Plasma membrane | 3.24E-08 |
| GO:0016020 | 97 | Membrane | 1.09E-02 |
| GO MF | |||
| GO:0038023 | 70 | Signaling receptor activity | 5.11E-023 |
| GO:0004930 | 64 | G-protein coupled receptor activity | 5.42E-023 |
| GO:0004888 | 68 | Transmembrane signaling receptor activity | 1.3E-022 |
| GO:0004871 | 72 | Signal transducer activity | 1E-021 |
| GO:0004872 | 70 | Receptor activity | 4.63E-021 |
| GO:0060089 | 72 | Molecular transducer activity | 5.95E-020 |
| GO:0004984 | 50 | Olfactory receptor activity | 1.39E-019 |
| KEGG | |||
| KEGG:04740 | 42 | Olfactory transduction | 6.46E-014 |
| KEGG:05144 | 5 | Malaria | 1.96E-02 |