Figure 1.

LSMean Changes of HAM-D Retardation Subscale Scores. The efficacy of duloxetine on HAM-D retardation subscale score was examined in comparison to placebo. The HAM-D retardation subscale consists of the following four items: Item 1 – depressed mood, Item 7 – work and activities, Item 8 – retardation, Item 14 – genital symptoms. These analyses were performed with MMRM. *p < 0.05, **p < 0.001, ***p < 0.0001. HAM-D, Hamilton Depression Rating Scale; LSMean, least squares mean; MMRM, mixed model repeated measures; n, number of patients