Table 3.

Patient disposition

Patient disposition	Duloxetine (N = 1555)	Placebo (N = 1206)	p-value
Early discontinuation, n (%)	371 (23.9)	344 (28.5)	0.005
Reasons for early discontinuations,n (%)
Adverse events	126 (8.1)	56 (4.6)	0.003
Patient decision	82 (5.3)	74 (6.1)	0.196
Lost to follow-up	64 (4.1)	59 (4.9)	0.203
Lack of efficacy	50 (3.2)	119 (9.9)	< 0.0001
Protocol violation	36 (2.3)	22 (1.8)	0.523
Physician decision	9 (0.6)	9 (0.7)	0.500
Sponsor decision	2 (0.1)	3 (0.2)	0.419
Death	1 (< 0.1)	1 (< 0.1)	0.822
Other	1 (< 0.1)	1 (< 0.1)	0.822

N, total number of patients; n, number of affected patients.