Table 4.
Mean value of variables for each group adjusted for repeat measurements on the same patient
| Asymptomatic (n = 298) | Symptomatic (n = 113) | Intervention (n = 45) | |
|---|---|---|---|
| UF volume (L) | 2.23 (0.11) | 2.43 (0.13), P = 0.02 | 2.24 (0.14), P = 0.91 |
| Adjusted UF volume (% of dry weight) | 3.00 (0.15) | 3.24 (0.17), P = 0.03 | 2.99 (0.19), P = 0.98 |
| Lowest blood volume (% reduction) | −9.32 (0.45) | −9.69 (0.64), P = 0.57 | −8.53 (0.85), P = 0.36 |
| Baseline SBP (mmHg) | 139.5 (2.6) | 139.4 (3.1), P = 0.97 | 141.1 (3.7), P = 0.62 |
| Minimum SBP (mmHg) | 111.2 (2.3) | 104.8 (2.8), P = 0.006 | 102.4 (3.4), P = 0.003 |
| Delta SBP (% of baseline SBP) | 0.20 (0.01) | 0.24 (0.02), P = 0.007 | 0.27 (0.02), P < 0.001 |
| Delta SBP over 15 min (mmHg) | 26.1 (1.2) | 27.5 (1.3), P < 0.52 | 29.4 (1.3), P < 0.63 |
| Delta SBP over 15 min (% of baseline SBP) | 0.19 (0.01) | 0.2 (0.001), P = 0.70 | 0.2 (0.02), P = 0.8 |
| Baseline DBP (mmHg) | 78.2 (1.8) | 78.4 (2.1), P = 0.90 | 82.0 (2.5), P = 0.08 |
| Minimum DBP (mmHg) | 59.4 (1.5) | 59.7 (1.8), P = 0.29 | 57.5 (2.2), P = 0.29 |
| Delta DBP (% of baseline DBP) | 0.23 (0.01) | 0.25 (0.02), P = 0.21 | 0.29 (0.02), P = 0.01 |
| Delta DBP over 15 min (mmHg) | 20.6 (1.3) | 20.7 (1.8), P = 0.98 | 22.9 (2.3), P = 0.32 |
| Delta DBP over 15 min (% of baseline DBP) | 0.28 (0.02) | 0.27 (0.03), P = 0.73 | 0.27 (0.04), P = 0.81 |
| Baseline MAP (mmHg) | 98.6 (1.8) | 98.7 (2.2), P = 0.94 | 101.7 (2.6), P = 0.17 |
| Minimum MAP (mmHg) | 79.1 (1.9) | 75.4 (2.0), P = 0.023 | 74.3 (2.8), P = 0.021 |
| Delta MAP (% of baseline MAP) | 0.19 (0.01) | 0.23 (0.02), P = 0.021 | 0.27 (0.02), P < 0.001 |
| Delta MAP over 15 min (mmHg) | 18.8 (1.1) | 20.4 (1.5), P = 0.29 | 22.9 (2.3), P = 0.32 |
| Delta MAP over 15 min (% of baseline MAP) | 0.19 (0.01) | 0.21 (0.02), P = 0.32 | 0.2 (0.02), P = 0.90 |
| Rate of SBP change in first hour (mmHg/h) | −7.1 (0.5) | −7.1 (0.5), P = 0.76 | −7.2 (0.5), P = 0.08 |
| Rate of DBP change in first hour (mmHg/h) | −3.9 (0.2) | −3.8 (0.2), P = 0.76 | −4.0 (0.2), P = 0.16 |
Results are expressed as mean (standard error) and P value for comparison with the asymptomatic group. Symptomatic vs. intervention comparisons were all nonsignificant at the 5% level.
DBP = diastolic blood pressure; MAP = mean arterial blood pressure; SBP = systolic blood pressure; UF = ultrafiltration.