Table 1.
Patient demographics and medical history
| Prophylaxis treatment N = 13 | On-demand treatment N = 4 | Total N = 17 | |
|---|---|---|---|
| Age, years, mean (min–max) | 23.2 (13–42) | 35.8 (27–46) | 26.1 (13–46) |
| <18 years, n (%) | 3 (23.1) | 0 | 3 (17.6) |
| Weight, kg, mean (min–max) | 64.1 (36.0–83.8) | 75.7 (62.4–93.0) | 66.8 (36.0, 93.0) |
| Race | |||
| White | 13 (100.0) | 4 (100.0) | 17 (100.0) |
| Previous exposure days to factor IX, mean (SD) | 861.9 (353.61) | 662.5 (131.50) | 815.0 (323.46) |
| Total bleeds 12 months prior to study entry, mean (SD) | 14.0 (17.97) | 27.0 (3.37) | 17.1 (16.63) |
| Spontaneous bleeds 12 months prior to study entry, mean (SD) | 9.2 (14.73) | 27.0 (3.37) | 13.4 (15.02) |
| Prior treatment | |||
| Prophylaxis, n (%) | 10 (76.9) | 0 | 10 (58.8) |
| On-demand, n (%) | 3 (23.1) | 4 (100.0) | 7 (41.2) |
| HIV, n (%) | 0 | 0 | 0 |
| HBV, n (%) | 0 | 1 (25.0) | 1 (5.9) |
| HCV, n (%) | 3 (23.1) | 2 (50.0) | 5 (29.4) |
| Haemophilic arthropathy, n (%) | 5 (38.5) | 4 (100.0) | 9 (52.9) |
| Synovitis, n (%) | 3 (23.1) | 0 | 3 (17.6) |
Min, minimum; max, maximum; n, number of patients.