Table 3.
Phenotypes caused by spatiotemporally regulated gene silencing
| Family of proteins/protein name | Protein/gene name | CG No. | Gal4 driver line | Glycans | ||||
|---|---|---|---|---|---|---|---|---|
| MS1096/A9 | SD | en | ptc | 69B | ||||
| N-acetylgalactosamine-4-O-sulfotransferase | d4ST2 | CG13937 | Extra vein | GAGs | ||||
| GAG glucuronyltransferase I | dGlcAT-I | CG32775 | Extra vein1 | |||||
| peptide-O-xylosyltransferase | dXylT/Oxt | CG32300 | Extra vein | Extra vein | ||||
| GAGβ1,4-galactosyltransferase I | dGAGβ4GalTI/β4GalT7 | CG11780 | Extra vein | Extra vein | ||||
| C5 epimerase | Heparan sulfate C5-epimerase | CG3194 | Extra vein | Extra vein | Extra vein2 | |||
| Hereditary multiple exostoses (EXT) protein | dExt1/Ttv | CG10117 | Extra vein3 | Extra vein | ||||
| Hereditary multiple exostoses (EXT) protein | dExt2/Stv | CG8433 | Extra vein | Extra vein | Extra vein | |||
| Hereditary multiple exostoses (EXT) protein | dExt3/Botv | CG15110 | Extra vein | acv deletion | ||||
| β1,3-glucuronyltransferase | dGlcAT-BSII/GlcAT-P | CG6207 | Extra vein | |||||
| GAGβ1,3-galactosyltransferase II | dGAGβ3GalTII | CG8734 | Extra vein | |||||
| PAPS transporter | Sll | CG7623 | Extra vein | |||||
| Chondroitin 4-O-sulfotransferase | dC4ST | CG31743 | Extra vein | |||||
| Syndecan | dSdc | CG10497 | Thick vein | |||||
| Protein O-fucosyltransferase | OFut1 | CG12366 | Thick vein4 | Notch | ||||
| β1,3-N-acetylglucosaminyltransferase | Fng | CG10580 | Thick vein | Thick vein | Thick vein5 | |||
| UDP-sugar transporter | Frc | CG3874 | Thick vein | |||||
| α1,6-fucosyltransferase | dα6Fut/FucT6 | CG2448 | Thick vein | Depigmentation6 | Terminal | |||
| GDP-Fuc transporter (Golgi) | Gfr/Nac | CG9620 | Depigmentation7 | |||||
| UDP-Gal/UDP-GalNAc transporter | Csat | CG2675 | Depigmentation8 | |||||
| β1,3-N-acetylglucosaminyltransferase or β1,3-galactosyltransferase | dβ3GnT or GalT1 | CG33145 | Depigmentation9 | |||||
| Glucosylceramide synthase | dGlcCerT/GlcT-1 | CG6437 | Thick vein | Glycolipid | ||||
| UDP-GlcNAc:polypeptide O-β-N-acetylglucosaminyltransferase | dO-GnT/Sxc | CG10392 | Thick vein | pcv deletion | O-GlcNAc | |||
Number of abnormal wings/number of tested wings = 40/76 (1), 46/46 (2), 70/70 (3), 64/64 (4) and 8/8 (5).
Number of depigmented males/number of tested males = 66/79 (6), 5/15 (7), 45/175 (8) and 9/69 (9).