Table 2.

Islet product characteristics stratified by primary post-IAT outcome

	Insulin use status at 6 mos.
Characteristic	Independence	Partial dependence	Complete dependence	One-way ANOVA or Kruskal-Wallis test^a

	Mean (± SE)			p-value
Islet size index	0.71 (± 0.05)	0.83 (± 0.05)	1.00 (± 0.07)	0.07
Proportion >200 μm (%)	6.6 (± 1.5)	8.4 (± 0.8)	10.3 (± 0.9)	0.09
IPs/kg	5,785 (± 692)	4,624 (± 259)	2,569 (± 241)	0.001 ^**
IEs/kg	3,947 (± 284)	3,688 (± 195)	3,183 (± 133)	0.02^*
IPs transplanted	343,588 (± 45,590)	315,445 (± 25,316)	253,804 (± 17,015)	0.04^*
IEs transplanted	239,531 (± 30,306)	260,876 (± 24,356)	236,724 (± 14,586)	0.68
TV transplanted (mL)	11.1 (± 1.8)	10.4 (± 1.1)	8.7 (± 0.9)	0.31

Abbreviations: ANOVA, analysis of variance; IAT, islet autotransplant; IE, islet equivalent; IP, islet particle; kg, kilogram (recipient body weight); SE, standard error (of the mean); TV, tissue volume;

One-way ANOVA was used for comparisons in which the sample data were normally distributed (as confirmed by the D'Agostino-Pearson omnibus normality test), and the Kruskal-Wallis test was used when the sample data were not normally distributed;

p<0.05;

^**

p<0.01.