Fig. 7.
Effects of bumetanide treatment on coherences (A), correlations (B) and sociability and social novelty tests (C). A) Coherences. In both the PFC (top graph) and DH (bottom graph), rats treated with bumetanide did not differ in coherences from controls. Rats with ELS not treated with bumetanide had significantly higher coherences in both the PFC and DH than the controls and rats with ELS treated with bumetanide. B) Voltage correlation. Comparison of mean (top graph) and peak (bottom graph) correlations in controls, ELS rats without bumetanide treatment and ELS rats with bumetanide treatment. Correlations of the PFC and DH were compared to VH. C) Comparison of sociability test (top) and social novelty task (bottom) in control rats, rats with ELS seizures treated with bumetanide and rats with ELS seizures treated with bumetanide. * = p<0.05, ** =p<0.01, *** = p<0.0001.