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. 2013 Jun 1;1(1):5–12. doi: 10.12945/j.aorta.2013.13.007

Figure 3.

Figure 3.

Indomethacin reduces macrophage infiltration in aortic adventitia of mgR/mgR mice. F4/80 immunohistochemistry in representative aorta sections from WT, untreated and indomethacin treated mgR/mgR mice. Arrowheads indicate F4/80 positive cells. WT mice exhibited nearly no macrophage infiltrate in the aortic wall. Macrophage infiltrates aortic adventitia of mgR/mgR mice, whereas there are decreased macrophages in indomethacin-treated mgR/mgR mice. Scale bar indicates 50 μm. Inset bar indicates 25 μm. Quantitative analysis of F4/80 macrophage showed statistically significant differences between untreated and indomethacin treated mgR/mgR mice. Number of animals per group was five to six. **P < 0.01.