Table 2.

Summary of 6 cases that gliomatosis peritonei was diagnosed at secondary surgeries.

PT	Peritoneal findings at 1st surgery	Additional biopsies after 1st surgerya	Peritoneal findings at the same time as GP	Interval between 1st & 2nd surgeries	Reason for 2nd surgery	Chemotherapy before 2nd surgery	Chemoradiation after 2nd surgery	Follow-up duration after diagnosis of GP or gliomab	Additional findings
3c	NA	IT	GP	24 months	Disease progressiond	Yes, BEP and mored	Radiation	ANED, 68 months	NA
9	NA	NA	GP	182 months	Abdominal and pelvic paine	No	No	ANED, 1.5 months	NA
10c	IT, MT	MT (liver mass)	GP, MT	10 months	Residual masses (CT)	Yes, BEP 6 cycles	No	ANED, 36 months	GTSf
11	NA	NA	GP	4 months	FDG-avid lesion (PET-CT)	No	No	ANED, 11 months	Encephalitisg
12c	IT	NA	GP	4 months	Peritoneal thickening (CT)	Yes, BEP 3 cycles	Yes, interferon	AWD, 25 months	GTSh
15c	IT	NA	GP, glioma, IT, MT	6 months	Sheet-like nodularity along the peritoneum and omental cake (CT and MRI).	Yes, EP/PE 4 cycles	Yes, HIPEC and radiation	AWD, 4 months	NA

Abbreviations: PT = patient; NA = not available; GP = gliomatosis peritonei; MT = mature teratoma; IT = immature teratoma; BEP = bleomycin, etoposide, cisplatin; EP/PE = etoposide and cisplatin chemotherapy; ANED = alive with no evidence of disease; AWD = alive with disease; ADSU = alive disease status unknown; GTS = growing teratoma syndrome; FDG = fludeoxyglucose F 18; PET = positron emission tomography; CT = computerized tomography; MRI = magnetic resonance imaging; HIPEC = hyperthermic intraperitoneal chemotherapy.

^aBiopsies performed after the first surgery, but before the diagnosis of GP.

^bPlease refer to Table 1 for the follow-up duration after diagnosis of primary ovarian neoplasms.

^cPatients #3, #10, #12 and #15 had ascites. However, time course of development of ascites suggested its association with either primary ovarian neoplasm or metastatic immature teratoma.

^dBecause patient had disease progression while on BEP, she also received paclitaxel, ifosfamide, and cisplatin for 3 courses.

^eIt was unclear whether abdominal and pelvic pain was associated with gliomatosis peritonei or endometriosis. The patient was previously diagnosed with endometriosis clinically, but it was never confirmed by pathology. Endometriosis was not present in all available pathology specimen.

^fPatient developed growing teratoma syndrome after chemotherapy, and had multiple masses in the abdomen and pelvis. Biopsy of 7.5-centimeter liver mass showed mature teratoma.

^gPatient developed anti-NMDA receptor encephalitis.

^hAfter the secondary surgery, patient was diagnosed as growing teratoma syndrome. Follow-up CT scan showed bilateral subdiaphragmatic implants encasing the liver and spleen, and pelvic implants encasing the uterus and sigmoid colon.