Figure 3.

Suprarenal AAA 4 weeks after angiotensin-II (Ang-II) infusion in the apo-e^−/− mouse (top left) not present in a similar mouse treated with low-level laser irradiation (LLLI) (top right). Needle standard is 0.5 mm. Note hemorrhage into the wall in the macroscopic (upper left, arrow) and H&E section (lower left; arrow) of the suprarenal segment of a nontreated Ang-II-infused mouse. The immunofluorescent stained section (lower right) of the boxed-in area of transmural disruption shows marked infiltration of MAC-2+ macrophages (green) in the area of the fragmented media (red = α-actin positive smooth muscle cells). Reprinted with permission from Gavish et al., Lasers in Surgery and Medicine. 2012;44:664–674.