Fig 1. Various types of tumor volume measurements.

Comparison of various tumor volume measurement methods for 2,250 primary breast tumors (1a). Spheroid tumor volumes and ellipsoid tumor volumes for 2,250 tumors according to the largest tumor size (1b). The red and purple arrows indicate the cases with discordant ellipsoid volume estimation and tumor sizes. Although the tumor with purple arrow has smaller tumor diameter than the tumor with red arrow, it has higher tumor volume with the ellipsoid TV measurement.