Table 4. Haplotype frequencies of MICA, HLA-B and HLA-C in patients with and without ocular toxoplasmosis and its manifestation as primary or recurrent.
| Haplotypes | Patients without ocular toxoplasmosis (n = 149) | Patients with ocular toxoplasmosis (n = 148) | Patients with primary manifestation (n = 120) | Patients with recurrent manifestation (n = 28) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MICA | HLA | n | (%) | n | (%) | n | (%) | n | (%) | P-value | Pc | OR | IC (95%) |
| *002 | B*35 | 11 | 3.6 | 23 | 7.8 | 17 | 7.0 | 6 | 10.7 | 0.04 a vs. b | ns | 2.20 | 1.05–4.60 |
| *002 | B*53 | 14 | 4.7 | 6 | 2.0 | 4 | 1.7 | 2 | 3.6 | Ns | |||
| *004 | B*44 | 26 | 8.7 | 14 | 4.7 | 11 | 4.6 | 3 | 5.3 | Ns | |||
| *008 | B*07 | 19 | 6.3 | 10 | 3.3 | 8 | 3.3 | 2 | 3.5 | Ns | |||
| *009 | B*51 | 16 | 5.3 | 21 | 7.0 | 17 | 7.0 | 3 | 5.3 | Ns | |||
| *002 | C*04 | 25 | 8.3 | 30 | 9.8 | 22 | 9.2 | 8 | 14.3 | Ns | |||
| *004 | C*16 | 18 | 6.0 | 12 | 4.0 | 10 | 4.1 | 2 | 3.5 | Ns | |||
| *008 | C*07 | 36 | 12.0 | 17 | 5.7 | 16 | 6.6 | 1 | 1.7 | 0.009 a vs. b | ns | 0.44 | 0.22–0.76 |
| *009 | C*06 | 12 | 3.9 | 7 | 2.4 | 7 | 2.9 | 0 | 0.0 | ns | |||
| *016 | C*04 | 13 | 4.4 | 11 | 3.4 | 9 | 3.1 | 2 | 3.5 | ns | |||
ns: non-significant (when P-value >0.05)
a: Patients without ocular toxoplasmosis
b: Patients with ocular toxoplasmosis