Table 6. The relationship between the single nucleotide polymorphisms and the risk of CBP, stratified by gender.
| Groups | Male | OR(95% CI) | Female | OR(95% CI) | ORadj(95% CI) | ||
|---|---|---|---|---|---|---|---|
| Cases(%) a | Controls(%) a | Cases(%) a | Controls(%) a | ||||
| XRCC1 rs25487 | |||||||
| GG | 2(9.52) | 19(46.34) | 1.000 | 9(11.25) | 80(49.69) | 1.000 | 1.000 |
| GA | 7(33.33) | 13(31.71) | 5.115(0.914–28.640) | 33(41.25) | 58(36.02) | 5.057(2.248–11.378)** | 5.068(2.433–10.555) ** |
| AA | 12(57.14) | 9(21.95) | 12.667(2.328–68.926)** | 38(47.50) | 23(14.29) | 14.686(6.202–34.773)** | 14.207(6.581–30.671)** |
| GA+AA | 19(90.48) | 22(53.66) | 8.205(1.688–39.874)** | 71(88.75) | 81(50.31) | 7.791(3.647–16.647)** | 7.870(3.970–15.603) ** |
| XRCC1 rs25489 | |||||||
| GG | 19(95.00) | 33(80.49) | 1.000 | 66(81.48) | 137(86.16) | 1.000 | 1.000 |
| GA+AA | 1(5.00) | 8(19.51) | 0.217(0.025–1.872) | 15(18.52) | 22(13.84) | 1.415(0.690–2.905) | 1.066(0.552–2.057) |
| XRCC1 rs1799782 | |||||||
| CC | 9(42.86) | 28(68.29) | 1.000 | 42(51.85) | 91(56.88) | 1.000 | 1.000 |
| CT | 6(28.57) | 11(26.83) | 1.697(0.488–5.902) | 28(34.57) | 54(33.75) | 1.123(0.626–2.016) | 1.208(0.712–2.051) |
| TT | 6(28.57) | 2(4.88) | 9.333(1.593–54.672)* | 11(13.58) | 15(9.37) | 1.589(0.673–3.753) | 2.299(1.096–4.821)* |
| CT+TT | 12(57.14) | 13(31.71) | 2.872(0.969–8.508) | 39(48.15) | 69(43.12) | 1.225(0.716–2.094) | 1.448(0.898–2.335) |
| PPP1R13L rs1005165 | |||||||
| CC | 11(55.00) | 8(19.51) | 1.000 | 23(28.40) | 58(36.48) | 1.000 | 1.000 |
| CT | 4(20.00) | 18(43.90) | 0.162(0.039–0.666)* | 36(44.44) | 69(43.40) | 1.316(0.701–2.468) | 0.899(0.518–1.557) |
| TT | 5(25.00) | 15(36.59) | 0.242(0.062–0.946)* | 22(27.16) | 32(20.13) | 1.734(0.838–3.585) | 1.082(0.584–2.006) |
| CT+TT | 9(45.00) | 33(80.49) | 0.198(0.061–0.640)** | 58(71.60) | 101(63.52) | 1.448(0.810–2.589) | 0.972(0.590–1.601) |
| CD3EAP rs967591 | |||||||
| GG | 11(52.38) | 8(19.51) | 1.000 | 21(26.92) | 62(38.51) | 1.000 | 1.000 |
| GA | 4(19.05) | 18(43.90) | 0.162(0.039–0.666)* | 34(43.59) | 64(39.75) | 1.568(0.822–2.994) | 1.014(0.580–1.772) |
| AA | 6(28.57) | 15(36.59) | 0.291(0.078–1.082) | 23(29.49) | 35(21.74) | 1.940(0.942–3.995) | 1.212(0.658–2.232) |
| GA+AA | 10(47.62) | 33(80.49) | 0.220(0.070–0.698) ** | 57(73.08) | 99(61.49) | 1.700(0.940–3.074) | 1.204(0.722–2.006) |
| XPB/ERCC3 rs4150441 | |||||||
| GG | 4(20.00) | 17(41.46) | 1.000 | 23(28.40) | 60(37.74) | 1.000 | 1.000 |
| GA | 13(65.00) | 20(48.78) | 2.763(0.758–10.074) | 44(54.32) | 74(46.54) | 1.551(0.844–2.850) | 1.731(1.001–2.996) |
| AA | 3(15.00) | 4(9.76) | 3.188(0.501–20.298) | 14(17.28) | 25(15.72) | 1.461(0.649–3.290) | 1.648(0.785–3.456) |
| GA+AA | 16(80.00) | 24(58.54) | 2.833(0.804–9.984) | 58(71.60) | 99(62.26) | 1.528(0.856–2.729) | 1.714(1.015–2.895) |
| XPC rs2279017 | |||||||
| GG | 9(45.00) | 10(24.39) | 1.000 | 35(43.21) | 62(38.99) | 1.000 | 1.000 |
| GT | 9(45.00) | 22(53.66) | 0.455(0.138–1492) | 37(45.68) | 73(45.92) | 0.898(0.506–1.592) | 0.790(0.473–1.321) |
| TT | 2(10.00) | 9(21.95) | 0.247(0.042–1.460) | 9(11.11) | 24(15.09) | 0.664(0.278–1.587) | 0.541(0.249–1.176) |
| GT+TT | 11(55.00) | 31(75.61) | 0.582(0.183–1.855) | 46(56.79) | 97(61.01) | 0.840(0.488–1.446) | 0.786(0.481–1.285) |
| XPC rs2228001 | |||||||
| AA | 9(45.00) | 10(24.39) | 1.000 | 36(44.44) | 68(42.77) | 1.000 | |
| AC | 9(45.00) | 22(53.66) | 0.455(0.138–1.492) | 36(44.44) | 72(45.28) | 0.944(0.535–1.668) | 0.825(0.4951.374) |
| CC | 2(10.00) | 9(21.95) | 0.247(0.042–1.460) | 9(11.11) | 19(11.95) | 0.895(0.367–2.179) | 0.673(0.307–1.474) |
| AC+CC | 11(55.00) | 31(75.61) | 0.394(0.127–1.224) | 45(55.56) | 91(57.23) | 0.934(0.545–1.602) | 0.799(0.492–1.294) |
| XPF rs4781560 | |||||||
| TT | 14(70.00) | 29(70.73) | 1.000 | 46(56.79) | 94(59.12) | 1.000 | 1.000 |
| TC | 5(25.00) | 12(29.27) | 0.863(0.254–2.932) | 30(37.04) | 58(36.48) | 1.057(0.601–1.859) | 1.020(0.611–1.701) |
| CC | 1(5.00) | 0(0.00) | - | 5(6.17) | 7(4.40) | 1.460(0.439–4.849) | - |
| TC+CC | 6(30.00) | 12(29.27) | 1.036(0.322–3.335) | 35(43.21) | 65(40.88) | 1.100(0.640–1.891) | 1.089(0.666–1.779) |
a: The data are missing because the sequence could not be amplified.
*P< 0.05
**P< 0.01.