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. 2015 Dec 17;10(12):e0144758. doi: 10.1371/journal.pone.0144758

Fig 4. Flurbiprofen or fenofibrate did not shift ε-cleavage of wild type or mutant APP by western blot analyses.

Fig 4

By immunoprecipitation and western blot analyses, neither flurbiprofen nor fenofibrate altered the length of AICD peptides generated from crude membranes from wild type APP (A, B) or APP-V717F (C, D) expressing CHO cells. Similar results were obtained with GSM-1 in APP-V717F expressing cells (E, F). Results were expressed as averaged ± standard error (B: n = 4, D: n = 3, and F: n = 3 experiments).