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. 2015 Dec;47-48:32–39. doi: 10.1016/j.semcdb.2015.10.018

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© 2015 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 1 — Role of AS in mRNA stability, translational activity and subcellular localization. Top, examples of relevant AS topologies; mid, mature mRNA containing 5′ and 3′UTRs flanking the protein-coding ORF; bottom, downstream regulation outcomes of AS events in the corresponding regions.