Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
In vitro and in vivo released MZCL combination is active
| IC50 (95% confidence interval) | |||
|---|---|---|---|
| Test sample | Anti-HIV (nM) | Anti-HSV-2 (ng/mL) | Anti-HPV (ng/mL) |
| In vitro release eluent (control)* |
1.17 (0.98-1.4) 1.27 (0.7-2.3) |
637 (575-706) 496 (222-1108) |
49.56 (44.8-54.9) 20.3 (19-52.7) |
| Vaginal fluid (control)* |
0.5 (0.44-.56) 1.26 (0.62-2.57) |
659 (545-798) 438 (207-923) |
31.9 (30.6-33) 32 (25.9-40.5) |
Controls are pure API diluted in cell propagation media
