Fig. 3.

Large numbers of proteins were identified in each differential-centrifugation fraction. A: Venn diagram showing number of proteins [GenInfo (GI) numbers] identified in each fraction. B: proteins mapping to 6,766 unique official gene symbols were identified. Chart shows a breakdown of identified proteins with regard to previous identification at a transcript level (25) or in prior proteomic studies (4, 13, 19–21). In this study, 1,253 proteins, including many integral membrane proteins, were newly identified.