FIGURE 1.
Derivation of MR1 ligands from riboflavin synthesis. A, schematic display of the riboflavin biosynthesis pathway. ribH, lumazine synthase; X, hypothetical phosphatase. B, chemical formation of pyrimidines and ribityllumazines from condensation of small metabolites with 5-A-RU. 3,4-DH-2-B-4-P, 3,4-dihydroxy-2-butanone-4-phosphate.