TABLE 1.
Summary of metabolites that are more than 2-fold higher in multiple Abcc5−/− tissues compared to wild type tissues
m/z indicates mass to charge ratio. Rt indicates retention time.
| m/z | Rt | Elemental composition | Identity |
|---|---|---|---|
| min | |||
| 320.062 | 17.4 | C11H15NO10 | β-Citrylglutamic acid (β-citryl-Glu; BCG) |
| 449.105 | 21.0 | C16H22N2O13 | β-Citryldiglutamic acid (β-citryl-Glu-Glu; BCG2)a |
| 303.083 | 11.9 | C11H16N2O8 | N-Acetylaspartylglutamic acid ((Ac)Asp-Glu; NAAG) |
| 432.125 | 17.3 | C16H23N3O11 | N-Acetylaspartyldiglutamic acid ((Ac)Asp-Glu-Glu; NAAG2) |
| 318.095 | 5.0 | C11H17N3O8 | Asp-Gly-Glu |
| 373.010 | 9.0 | C13H18N4O9 | Succinylaminoimidazolecarboxamide riboside (SAICAr) |
| 289.086 | 3.7 | C11H18N2O5S | Unknown; contains sulfate moiety |
| 421.055 | 18.5 | Unknown | Unknown |
| 456.175 | 13.5 | Unknown | Unknown |
a Putative identification; reference standard is not available.