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. 2015 Oct 7;309(12):F1049–F1059. doi: 10.1152/ajprenal.00311.2015

Fig. 6.

Fig. 6.

Response to protamine sulfate and transforming growth factor-β1 (TGF-β1). A: response to protamine sulfate and TGF-β1. Time course of changes in fluorescence in glomeruli isolated from control SD rats and treated with protamine sulfate (right) or TGF-β1 (left) are shown. B: effect of protamine sulfate (right) and TGF-β1 (left) on permeability of the glomerulus to albumin (Palb) of isolated glomeruli. All glomeruli were isolated and stored on ice in isotonic HBSS solution with 6% BSA. The glomeruli in the protamine sulfate experiments were studied at room temperature while the glomeruli in the TGF-β1 experiments were incubated with TGF-β1 or vehicle for 15 min at 37°C before study. Values are means ± SE. Numbers in parentheses indicate the number of SD rats and glomeruli studied per group. *Significant difference (P < 0.05) compared with the corresponding value in the control glomeruli treated with vehicle.