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. 2015 Oct 14;309(12):F1035–F1048. doi: 10.1152/ajprenal.00253.2015

Fig. 1.

Fig. 1.

Cyclooxygenase (COX) expression in COX-2 knockout (COX-2−/−) and wild-type (WT) mice subjected to unilateral ureteral obstruction (UUO). A: cortical COX-2 mRNA expression in response to 3 days of UUO (3dUUO; n = 5). B: cortical COX-2 mRNA expression in response to 7 days of UUO (7dUUO). COX-2 mRNA expression was normalized to GAPDH (n = 4). C: cortical COX-1 protein abundance in response to 3 days of UUO (n = 6). D: cortical COX-1 protein abundance in response to 7 days of UUO (n = 6). E: inner medullary COX-1 protein abundance in response to 3 days of UUO (n = 6). F: inner medullary COX-1 protein abundance in response to 7 days of UUO (n = 6). COX-1 protein abundance was normalized to total protein. Sham, sham-operated animals. Data are presented as means ± SE. *P < 0.05; **P < 0.01; ***P < 0.001.